| ncRNA name | MMP2 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells |
| Methods | siRNA transfection, Gelatin zymography, Western blot, semi-qPCR, ELISA, immunohistochemical analysis |
| Expression pattern | associated |
| Functional description | Inhibition of MMP2 ameliorated glucose-induced increase in mitochondrial superoxide and membrane permeability, prevented cytochrome c leakage from the mitochondria, and inhibited capillary cell apoptosis. |
| PubMed ID | 20479714 |
| Year | 2010 |
| Title | Matrix metalloproteinase-2 in the development of diabetic retinopathy and mitochondrial dysfunction. |
| Drug-related ncRNA | NO |
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